Page 67 - CIBERES2016-ENG

Most relevant scientific articles
• Masa J.F., Corral J., Caballero C., Barrot E., Teran-Santos J., Alonso-alvarez M.L. et al. Non-invasive ventilation in obesity hypoventilation syndrome without severe obstructive sleep apnoea. Thorax. 2016.
• Khalyfa A., Kheirandish-Gozal L., Khalyfa A.A., Philby M.F., Alonso-Alvarez M.L., Mohammadi M. et al. Circulating plasma extracellular microvesicle MicroRNA cargo and endothelial dysfunction in children with obstructive sleep apnea. American Journal of Respiratory and Critical Care Medicine. 2016;194(9):1116-1126.
• Campos-Rodriguez F., Queipo-Corona C., Carmona-Berna C., Jurado-Gamez B., Cordero-Guevara J., Reyes-Nunez N. et al. Continuous positive airway pressure improves quality of life in women with obstructive sleep apnea a randomized controlled trial. American Journal of Respiratory and Critical Care Medicine. 2016;194(10):1286-1294.
• Kaditis AG, Alonso Alvarez ML, Boudewyns A, Alexopoulos EI, Ersu R, Joosten K et al. Obstructive sleep disordered breathing in 2- to 18-year-old children: diagnosis and management.The European respiratory journal. 2016;47(1):69-94.
• Masa JF, Corral J, Romero A, Caballero C, Terán-Santos J, Alonso-Álvarez ML et al. Protective cardiovascular effect of sleep apnea severity in obesity hypoventilation syndrome.Chest. 2016.
Highlights
PROJECTS
• “Eficacia de la VNI ajustada automáticamente en el SHO” “ funded by FIS and Philips with 270,000€. Currently running.
• “iREST” “Improving obstructive sleep apnea therapy through a personalised telematic intervention” and “3DREST” 3 dimensional telematic intervention to improve obstructive sleep apnea therapy”. Both projects were presented in April and in October Horizonte 2020 applications.
• Anticipate “A study comparing the current COPD intervention with a technology-assisted responsive and integrated approach to Prevent hospitalizations due to acute exacerbations” was presented in October Horizonte 2020 applications.
EVENTS
• V International Symposium “COPD and Tobacco”: diagnostic-therapeutic update and future perspectives. Cáceres 10, 11 November 2016.
RESULTS
• From a multicentric, non-inferiority, cost-effectiveness, randomized controlled trial: Conventional polysomnography is not necessary in obstructive sleep apnea syndrome management. This finding could change established clinical practice, with a clear economic benefit. Presently in the second revision in Am J Respir Crit Care Med.
• From PICKWICK multicentric, randomized controlled trial: Echocardiographic changes with positive airway pressure modalities in obesity hypoventilation syndrome. Medium-term NIV therapy in patients with OHS is more effective than CPAP and lifestyle modification in improving pulmonary artery pressure and measures of LV hypertrophy. Presently the paper is ongoing.
GUIDELINES
• ERS Task Force on Technical Standards for the Scoring of Respiratory events using Type III devices for the diagnosis of Sleep Disordered Breathing. JF Masa is member of the writing committee.
• ATS guidelines: Obesity hypoventilation syndrome: Evidence-based guidelines for evaluation and management. JF Masa is the co-chairman.
research groups 67
• Sleep apnea and driving. Recommendations for the interpretation of Annex IV of the General Regulations of Drivers approved by R.D. 818/2009, as amended by the R.D. 1055/2015. JF Masa has been member (Arch Bronchoneumol in press).
RES