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leaD researcher
Nieto Martín, Amelia
agencia estatal consejo Superior de Investigaciones Científicas
Centro Nacional de Biotecnología.
Universidad Autónoma de Madrid. Cantoblanco. Dpto. de Biología Molecular y Celular. c/ Darwin, 3 · 28049 Madrid
(+34) 91 585 49 14 [email protected] group website
GROUP MEMBERS
Staff members: Marcos Villar, Laura | Pazo Fernández, Alejandra
Associated members: Falcón Escalona, Ana | Melero Fontdevila, José Antonio
Main lines of research
• Mechanism of influenza virus interaction with the host cell.
• Mecahnisms of pathogeinicity of influenza virus.
• Study of human respiratory syncityal virus and metapneuomovirus glycoproteins.
Most relevant scientific articles
• Rodriguez-Frandsen A., De Lucas S., Perez-Gonzalez A., Perez-Cidoncha M., Roldan-Gomendio A., Pazo A. et al. HCLE/C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles. Scientific Reports. 2016;6.
• Marcos-Villar L., Pazo A., Nieto A. Influenza virus and chromatin: Role of the CHD1 chromatin remodeler in the virus life cycle. Journal of Virology. 2016;90(7):3694-3707.
• Mas V., Rodriguez L., Olmedillas E., Cano O., Palomo C., Terron M.C. et al. Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation. PLoS Pathogens. 2016;12(9).
• Rodriguez P., Perez-Morgado M.I., Gonzalez V.M., Martin M.E., Nieto A. Inhibition of Influenza Virus Replication by DNA Aptamers Targeting a Cellular Component of Translation Initiation. Molecular Therapy - Nucleic Acids. 2016;5.
• Landeras-Bueno S., Fernandez Y., Falcon A., Oliveros J.C., Ortin J. Chemical genomics identifies the PERK-mediated unfolded protein stress response as a cellular target for influenza virus inhibition. mBio. 2016;7(2).
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PROGRAMMES
Infectious Respiratory Diseases