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PET radiotracers for nuclear imaging. Finally, the group also has a long experience in the application of metabolic analysis to the study of different pathologies, by the use of Magnetic Resonance Spectroscopy and Mass Spectrometry and different statistical tools developed within the group. Our research projects range from technical developments and chemistry advances to in vitro studies and tracking biological processes in vivo.
Most relevant scientific articles
• Santos A., Rivas E., Rodriguez-Roisin R., Sanchez M., Ruiz-Cabello J., Arismendi E. et al. Lung Tissue Volume is Elevated in Obesity and Reduced by Bariatric Surgery. Obesity Surgery. 2016;1-8.
• Perez-Medina C., Abdel-Atti D., Tang J., Zhao Y., Fayad Z.A., Lewis J.S. et al. Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy. Nature Communications. 2016;7.
• Latorre-Pellicer A., Moreno-Loshuertos R., Lechuga-Vieco A.V., Sanchez-Cabo F., Torroja C., Acin-Perez R. et al. Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing. Nature. 2016;535(7613):561-565.
• Bujak R., Mateo J., Blanco I., Izquierdo-Garcia J.L., Dudzik D., Markuszewski M.J. et al. New biochemical insights into the mechanisms of pulmonary arterial hypertension in humans. PLoS ONE. 2016;11(8).
• Chamorro V., Pandolfi R., Moreno L., Barreira B., Martinez-Ramas A., Morales-Cano D. et al. Effects of quercetin in a rat model of hemorrhagic traumatic shock and reperfusion. Molecules. 2016;21(12).
Highlights
The group participates in a project funded by the Foundation Against Pulmonary Hypertension “Beca Actelion” presented and obtained by Dr. Pérez Vizcaino as Principal Investigator. During this year 2016, we have obtained another initiative joint project with other members of Ciberes, such as the project awarded by the Department of Health of the Government of Navarra obtained from Dr. Junkal Garmendia García. The different research members that constitutes the group 31 have obtained two more projects in 2016, funded respectively by the Carlos III Health Institute (PI-DTS-2016-0059) within the technological innovation program and another from the Ministry of Economy and Competitiveness (SAF2016- 79593-P).
We have presented different proposals to the H2020 framework, e.g. an ERA-NET (Euronanomed) as coordinators and to a ERC-Advanced program. Finally, in collaboration with the group of Dr. Germán Peces- Barba and a group from the Massachusetts General Hospital of Boston we have presented a joint initiative to the ROI call from the USA National Institutes of Health.
From the technological aspects of our research, we have filed for an European patent for methodology of erythrocyte labeling as a Positron Emission Tomography (PET)-based diagnostic tool with special relevance in the field of pulmonary hypertension and respiratory distress.
RES
research groups 89